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Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression.

H2dl808 is a defective deletion mutant of human adenovirus 2 lacking most of transcriptional early region 4. Although the mutant can be grown in the complementing cell line W162, it is defective in human cell lines normally used to propagate adenovirus. In such nonpermissive cells, H2dl808 exhibits...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Weinberg, D H, Ketner, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3485200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.3.833-838.1986
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