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The Carboxy-Terminal Region of apoA-I is Required for the ABCA1-Dependent Formation of α-HDL but not preβ-HDL Particles In Vivo
ABCA1-mediated lipid efflux to lipid poor apoA-I results in the gradual lipidation of apoA-I. This leads to the formation of discoidal HDL which are subsequently converted to spherical HDL by the action of LCAT. We have investigated the effect of point mutations and deletions in the carboxy-terminal...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2528067/ https://ncbi.nlm.nih.gov/pubmed/17447731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi602354t |
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