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Stochastic hybrid modeling of DNA replication across a complete genome

DNA replication in eukaryotic cells initiates from hundreds of origins along their genomes, leading to complete duplication of genetic information before cell division. The large number of potential origins, coupled with system uncertainty, dictates the need for new analytical tools to capture spati...

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Bibliografske podrobnosti
Main Authors: Lygeros, J., Koutroumpas, K., Dimopoulos, S., Legouras, I., Kouretas, P., Heichinger, C., Nurse, P., Lygerou, Z.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527905/
https://ncbi.nlm.nih.gov/pubmed/18713859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805549105
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