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Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization.

Herpesvirus saimiri L-DNA sequences between 0.0 and 4.0 map units (4.5 kilobase pairs) are required for oncogenicity; these sequences are not required for replication of the virus. To investigate the basis for the lack of oncogenicity of mutants with deletions in this region and to study the functio...

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Bibliographic Details
Published in:J Virol
Main Authors: Desrosiers, R C, Silva, D P, Waldron, L M, Letvin, N L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.2.701-705.1986
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