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Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization.

Herpesvirus saimiri L-DNA sequences between 0.0 and 4.0 map units (4.5 kilobase pairs) are required for oncogenicity; these sequences are not required for replication of the virus. To investigate the basis for the lack of oncogenicity of mutants with deletions in this region and to study the functio...

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Autors principals: Desrosiers, R C, Silva, D P, Waldron, L M, Letvin, N L
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC252789/
https://ncbi.nlm.nih.gov/pubmed/3003401
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