PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

Phosphorylation of histone H2AX on Ser 139 (γH2AX) is one of the earliest events in the response to DNA double-strand breaks; however, the subsequent removal of γH2AX from chromatin is less understood, despite being a process tightly coordinated with DNA repair. Previous studies in yeast have identi...

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Bibliografiske detaljer
Main Authors: Nakada, Shinichiro, Chen, Ginny I, Gingras, Anne-Claude, Durocher, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527856/
https://ncbi.nlm.nih.gov/pubmed/18758438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.162
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