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Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat

The aged heart sustains greater injury during ischemia (ISC) and reperfusion (REP) compared to the adult heart. In the Fischer 344 (F344) rat, aging decreases oxidative phosphorylation and complex III activity increasing the production of reactive oxygen species in interfibrillar mitochondria (IFM)...

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Bibliografiske detaljer
Main Authors: Lesnefsky, Edward J., Hoppel, Charles L.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527751/
https://ncbi.nlm.nih.gov/pubmed/18515061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2008.05.444
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