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A reduction of cytochrome c mediates an age-related decline of oxidative phosphorylation in rat kidney mitochondria

Kidney function declines with advancing age and mitochondria have been implicated. We have examined the integrated function of mitochondria isolated from kidneys of 6 and 24 month Fischer 344 rats. Oxidative phosphorylation (OXPHOS) of intact mitochondria and cytochrome c oxidase activity in permeab...

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Autori principali: O’Toole, John F., Patel, Hiral V., Naples, Colin J., Fujioka, Hisashi, Hoppel, Charles L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759985/
https://ncbi.nlm.nih.gov/pubmed/20100174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091373
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