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Functional Copy-Number Alterations in Cancer

Understanding the molecular basis of cancer requires characterization of its genetic defects. DNA microarray technologies can provide detailed raw data about chromosomal aberrations in tumor samples. Computational analysis is needed (1) to deduce from raw array data actual amplification or deletion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Taylor, Barry S., Barretina, Jordi, Socci, Nicholas D., DeCarolis, Penelope, Ladanyi, Marc, Meyerson, Matthew, Singer, Samuel, Sander, Chris
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527508/
https://ncbi.nlm.nih.gov/pubmed/18784837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003179
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