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Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents

In an ongoing effort to develop new and potent antituberculosis agents, a second generation series of nitrofuranyl amides was synthesized based on the lead compound 5-nitro-furan-2-carboxylic acid 3,4-dimethoxy-benzylamide. The primary design consideration was to improve the solubility and consequen...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Tangallapally, Rajendra P., Yendapally, Raghunandan, Lee, Robin E., Lenaerts, Anne J.M., Lee, Richard E.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527484/
https://ncbi.nlm.nih.gov/pubmed/16366608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm050765n
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