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Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents
In an ongoing effort to develop new and potent antituberculosis agents, a second generation series of nitrofuranyl amides was synthesized based on the lead compound 5-nitro-furan-2-carboxylic acid 3,4-dimethoxy-benzylamide. The primary design consideration was to improve the solubility and consequen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527484/ https://ncbi.nlm.nih.gov/pubmed/16366608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm050765n |
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