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Activation of the p42 Mitogen-activated Protein Kinase Pathway Inhibits Cdc2 Activation and Entry into M-Phase in Cycling Xenopus Egg Extracts

We have added constitutively active MAP kinase/ERK kinase (MEK), an activator of the mitogen-activated protein kinase (MAPK) signaling pathway, to cycling Xenopus egg extracts at various times during the cell cycle. p42MAPK activation during entry into M-phase arrested the cell cycle in metaphase, a...

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Bibliografiska uppgifter
Huvudupphovsmän: Bitangcol, John C., Chau, Andrew S.-S., Stadnick, Ellamae, Lohka, Manfred J., Dicken, Bryan, Shibuya, Ellen K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC25274/
https://ncbi.nlm.nih.gov/pubmed/9450967
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