Impaired CD4(+) and CD8(+) T cell phenotype and reduced chemokine secretion in recent-onset type 1 diabetic children

Although the role of the T cell-mediated autoimmune reaction in type 1 diabetes (T1D) is conclusive, studies including data from human circulating CD4(+) and CD8(+) lymphocytes subsets during the disease onset and posterior development are scarce. Further, chemokines and chemokine receptors are key...

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Bibliographische Detailangaben
Hauptverfasser: Hedman, M, Faresjö, M, Axelsson, S, Ludvigsson, J, Casas, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2008
Schlagworte:
Translational Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527367/
https://ncbi.nlm.nih.gov/pubmed/18803760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03720.x
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