Effective Chemokine Secretion by Dendritic Cells and Expansion of Cross-Presenting CD4(−)/CD8(+) Dendritic Cells Define a Protective Phenotype in the Mouse Model of Coxsackievirus Myocarditis

Enteroviruses such as coxsackievirus B3 (CVB3) are able to induce lethal acute and chronic myocarditis. In resistant C57BL/6 mice, CVB3 myocarditis is abrogated by T-cell-dependent mechanisms, whereas major histocompatibility complex (MHC)-matched permissive A.BY/SnJ mice develop chronic myocarditis...

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Bibliographische Detailangaben
Hauptverfasser: Weinzierl, Andreas Oliver, Szalay, Gudrun, Wolburg, Hartwig, Sauter, Martina, Rammensee, Hans-Georg, Kandolf, Reinhard, Stevanović, Stefan, Klingel, Karin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519575/
https://ncbi.nlm.nih.gov/pubmed/18550677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00047-08
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