The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

The amyloid β-peptide (Aβ) has been suggested to exert its toxicity intracellularly. Mitochondrial functions can be negatively affected by Aβ and accumulation of Aβ has been detected in mitochondria. Because Aβ is not likely to be produced locally in mitochondria, we decided to investigate the mecha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hansson Petersen, Camilla A., Alikhani, Nyosha, Behbahani, Homira, Wiehager, Birgitta, Pavlov, Pavel F., Alafuzoff, Irina, Leinonen, Ville, Ito, Akira, Winblad, Bengt, Glaser, Elzbieta, Ankarcrona, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527349/
https://ncbi.nlm.nih.gov/pubmed/18757748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806192105
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