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Identifying Fragilities in Biochemical Networks: Robust Performance Analysis of Fas Signaling-Induced Apoptosis

Proper control of apoptotic signaling is critical to immune response and development in multicellular organisms. Two tools from control engineering are applied to a mathematical model of Fas ligand signaling-induced apoptosis. Structured singular value analysis determines the volume in parameter spa...

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Bibliografiske detaljer
Main Authors: Shoemaker, Jason E., Doyle, Francis J.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527273/
https://ncbi.nlm.nih.gov/pubmed/18539637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.123398
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