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The JAK-STAT Signaling Network in the Human B-Cell: An Extreme Signaling Pathway Analysis

Large-scale models of signaling networks are beginning to be reconstructed and corresponding analysis frameworks are being developed. Herein, a reconstruction of the JAK-STAT signaling system in the human B-cell is described and a scalable framework for its network analysis is presented. This approa...

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Detalhes bibliográficos
Main Authors: Papin, Jason A., Palsson, Bernhard O.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304358/
https://ncbi.nlm.nih.gov/pubmed/15240442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.029884
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