The Effect of Cholesterol on Short- and Long-Chain Monounsaturated Lipid Bilayers as Determined by Molecular Dynamics Simulations and X-Ray Scattering

We investigate the structure of cholesterol-containing membranes composed of either short-chain (diC14:1PC) or long-chain (diC22:1PC) monounsaturated phospholipids. Bilayer structural information is derived from all-atom molecular dynamics simulations, which are validated via direct comparison to x-...

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Detalhes bibliográficos
Main Authors: Kučerka, Norbert, Perlmutter, Jason D., Pan, Jianjun, Tristram-Nagle, Stephanie, Katsaras, John, Sachs, Jonathan N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Membranes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527263/
https://ncbi.nlm.nih.gov/pubmed/18515383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.122465
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