Alamethicin in Lipid Bilayers: Combined use of X-ray Scattering and MD Simulations

We study fully hydrated bilayers of two di-monounsaturated phospholipids diC18:1PC (DOPC) and diC22:1PC with varying amounts of alamethicin (Alm). We combine the use of X-ray diffuse scattering and molecular dynamics simulations to determine the orientation of alamethicin in model lipids. Comparison...

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Autori principali: Pan, Jianjun, Tieleman, D. Peter, Nagle, John F., Kucerka, Norbert, Tristram-Nagle, Stephanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693350/
https://ncbi.nlm.nih.gov/pubmed/19248763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.02.013
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