Voltage-Dependent C-Type Inactivation in a Constitutively Open K(+) Channel

Most voltage-gated potassium (Kv) channels undergo C-type inactivation during sustained depolarization. The voltage dependence and other mechanistic aspects of this process are debated, and difficult to elucidate because of concomitant voltage-dependent activation. Here, we demonstrate that MinK-KCN...

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Bibliographic Details
Main Authors: Panaghie, Gianina, Purtell, Kerry, Tai, Kwok-Keung, Abbott, Geoffrey W.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Channels, Receptors, and Electrical Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527255/
https://ncbi.nlm.nih.gov/pubmed/18567635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133678
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