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Use of monoclonal antibodies to identify four neutralization immunogens on a common cold picornavirus, human rhinovirus 14.

A collection of 35 mouse monoclonal antibodies, raised against human rhinovirus 14 (HRV-14), was used to isolate 62 neutralization-resistant mutants. When cross-tested against the antibodies in a neutralization assay, the mutants fell into four antigenic groups, here called neutralization immunogens...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Sherry, B, Mosser, A G, Colonno, R J, Rueckert, R R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1986
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2416951/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.1.246-257.1986
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