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Antibodies that block rhinovirus attachment map to domain 1 of the major group receptor.

The vast majority of human rhinovirus serotypes utilize the intercellular adhesion molecule 1 (ICAM-1) as the attachment site on susceptible cells. Twelve murine monoclonal antibodies were isolated and shown by competition binding studies to recognize three distinct, nonoverlapping epitopes on the I...

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Autors principals: Lineberger, D W, Graham, D J, Tomassini, J E, Colonno, R J
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC249435/
https://ncbi.nlm.nih.gov/pubmed/1970837
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