Distinct Role of Long 3′UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

The brain produces two brain-derived neurotrophic factor (BDNF) transcripts, with either short or long 3′ untranslated regions (3′UTR). The physiological significance of the two forms of mRNAs encoding the same protein is unknown. Here we show that the short and long 3′UTR BDNF mRNAs are involved in...

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Detalhes bibliográficos
Main Authors: An, Juan Ji, Gharami, Kusumika, Liao, Guey-Ying, Woo, Newton H., Lau, Anthony G., Vanevski, Filip, Torre, Enrique R., Jones, Kevin R., Feng, Yue, Lu, Bai, Xu, Baoji
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527207/
https://ncbi.nlm.nih.gov/pubmed/18614020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.045
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