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Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

Mutations in the Bdnf gene, which produces transcripts with either short or long 3′ untranslated regions (3′UTRs), cause human obesity; however, the precise role of BDNF in the regulation of energy balance remains unknown. Here we show the relationship between long 3′UTR Bdnf mRNA, leptin, neuronal...

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Detalhes bibliográficos
Main Authors: Liao, Guey-Ying, An, Juan Ji, Gharami, Kusumika, Waterhouse, Emily G., Vanevski, Filip, Jones, Kevin R., Xu, Baoji
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327556/
https://ncbi.nlm.nih.gov/pubmed/22426422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2687
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