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Overexpression of the Matrix Metalloproteinase Matrilysin Results in Premature Mammary Gland Differentiation and Male Infertility

To examine the role of matrilysin (MAT), an epithelial cell-specific matrix metalloproteinase, in the normal development and function of reproductive tissues, we generated transgenic animals that overexpress MAT in several reproductive organs. Three distinct forms of human MAT (wild-type, active, an...

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Auteurs principaux: Rudolph-Owen, Laura A., Cannon, Paul, Matrisian, Lynn M.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC25271/
https://ncbi.nlm.nih.gov/pubmed/9450965
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