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Protein folding kinetics: barrier effects in chemical and thermal denaturation experiments

Recent experimental work on fast protein folding brings about an intriguing paradox. Microsecond-folding proteins are supposed to fold near or at the folding speed limit (downhill folding), but yet their folding behavior seems to comply with classical two-state analyses, which imply the crossing of...

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Detalhes bibliográficos
Main Authors: Naganathan, Athi N., Doshi, Urmi, Muñoz, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527040/
https://ncbi.nlm.nih.gov/pubmed/17419630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0689740
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