Mutations conferring resistance to neutralization with monoclonal antibodies in type 1 poliovirus can be located outside or inside the antibody-binding site.

Antigenic variants resistant to eight neutralizing monoclonal antibodies were selected from wild (Mahoney) and attenuated (Sabin) type 1 infectious poliovirions. Cross-immunoprecipitation revealed interrelationships between epitopes which were not detected by cross-neutralization. Operational analys...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Blondel, B, Crainic, R, Fichot, O, Dufraisse, G, Candrea, A, Diamond, D, Girard, M, Horaud, F
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1986
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2416957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.1.81-90.1986
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