Mutations conferring resistance to neutralization with monoclonal antibodies in type 1 poliovirus can be located outside or inside the antibody-binding site.

Antigenic variants resistant to eight neutralizing monoclonal antibodies were selected from wild (Mahoney) and attenuated (Sabin) type 1 infectious poliovirions. Cross-immunoprecipitation revealed interrelationships between epitopes which were not detected by cross-neutralization. Operational analys...

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Detaylı Bibliyografya
Asıl Yazarlar: Blondel, B, Crainic, R, Fichot, O, Dufraisse, G, Candrea, A, Diamond, D, Girard, M, Horaud, F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1986
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC252701/
https://ncbi.nlm.nih.gov/pubmed/2416957
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