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Concise, Asymmetric, Stereocontrolled Total Synthesis of Stephacidins A, B and Notoamide B

Concise asymmetric total syntheses of the fungal metabolites (−)-stephacidin A, (+)-stephacidin B, and (+)-notoamide B are described. Key features of these total syntheses include (1) a facile synthesis of (R)-allyl proline methyl ester, (2) a revised route toward the pyranoindole ring system, (3) a...

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Autors principals: Artman, Gerald D., Grubbs, Alan W., Williams, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526546/
https://ncbi.nlm.nih.gov/pubmed/17455936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja070259i
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