Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-Phosphate/G(13) Pathway

Regulation of intracellular cyclic adenosine 3′,5′-mono-phosphate (cAMP) is integral in mediating cell growth, cell differentiation, and immune responses in hematopoietic cells. To facilitate studies of cAMP regulation we developed a BRET (bioluminescence resonance energy transfer) sensor for cAMP,...

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Hauptverfasser: Jiang, Lily I., Collins, Julie, Davis, Richard, Lin, Keng-Mean, DeCamp, Dianne, Roach, Tamara, Hsueh, Robert, Rebres, Robert A., Ross, Elliott M., Taussig, Ronald, Fraser, Iain, Sternweis, Paul C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526465/
https://ncbi.nlm.nih.gov/pubmed/17283075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609695200
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