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Protein Meta-Functional Signatures from Combining Sequence, Structure, Evolution, and Amino Acid Property Information

Protein function is mediated by different amino acid residues, both their positions and types, in a protein sequence. Some amino acids are responsible for the stability or overall shape of the protein, playing an indirect role in protein function. Others play a functionally important role as part of...

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Autors principals: Wang, Kai, Horst, Jeremy A., Cheng, Gong, Nickle, David C., Samudrala, Ram
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526173/
https://ncbi.nlm.nih.gov/pubmed/18818722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000181
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