Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4.

Eitemau Tebyg

• Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells.
  gan: Zhu, Z, et al.
  Cyhoeddwyd: (1996)
• Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.
  gan: Wu, N, et al.
  Cyhoeddwyd: (1996)
• Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient.
  gan: McCarthy, A M, et al.
  Cyhoeddwyd: (1989)
• Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.
  gan: DeLuca, N A, et al.
  Cyhoeddwyd: (1988)
• Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture.
  gan: Sacks, W R, et al.
  Cyhoeddwyd: (1987)