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Potent RNAi by short RNA triggers

RNA interference (RNAi) is a gene-silencing mechanism by which a ribonucleoprotein complex, the RNA-induced silencing complex (RISC) and a double-stranded (ds) short-interfering RNA (siRNA), targets a complementary mRNA for site-specific cleavage and subsequent degradation. While longer dsRNA are en...

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Detalles Bibliográficos
Main Authors: Chu, Chia-ying, Rana, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525957/
https://ncbi.nlm.nih.gov/pubmed/18658119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1161908
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