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Membrane Topology Of Human ASBT (SLC10A2) Determined By Dual Label Epitope Insertion Scanning Mutagenesis. New Evidence For Seven Transmembrane Domains

The membrane topology of the human apical sodium-dependent bile acid transporter (hASBT) remains unresolved. Whereas N-glycosylation analysis favors a 7 transmembrane (TM) model, membrane insertion scanning supports a 9TM topology. In order to resolve this controversy, we used dual label epitope ins...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Banerjee, Antara, Swaan, Peter W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525805/
https://ncbi.nlm.nih.gov/pubmed/16411770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052202j
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