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DOMINANT NEGATIVE MUTANTS OF TRANSDUCIN-α THAT BLOCK ACTIVATED RECEPTOR

Mutations counterpart to dominant negative RasSer17Asn in the α-subunits of heterotrimeric G-proteins are known to also produce dominant negative effects. The mechanism of these mutations remains poorly understood. Here, we examined the effects and mechanism of the Ser43Cys and Ser43Asn mutants of t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Natochin, Michael, Barren, Brandy, Artemyev, Nikolai O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525804/
https://ncbi.nlm.nih.gov/pubmed/16700559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060381e
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