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EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-γ and IL-2

Symptomatic primary Epstein-Barr virus (EBV) infection and elevated humoral immune responses to EBV are associated with an increased risk of developing multiple sclerosis (MS). We explored mechanisms leading to this change in EBV-specific immunity in untreated patients with MS and healthy virus carr...

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Autors principals: Lünemann, Jan D., Jelčić, Ilijas, Roberts, Susanne, Lutterotti, Andreas, Tackenberg, Björn, Martin, Roland, Münz, Christian
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525578/
https://ncbi.nlm.nih.gov/pubmed/18663124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072397
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