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Children with Endemic Burkitt Lymphoma are Deficient in EBNA1-Specific IFN-γ T Cell Responses

Endemic Burkitt lymphoma (eBL) is the most common childhood cancer in equatorial Africa and is linked to Epstein-Barr virus (EBV) and Plasmodium falciparum co-infections early in life. Epstein-Barr nuclear antigen 1 (EBNA1) is the sole viral latent antigen expressed in BL tumors. Loss of EBNA1-speci...

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Detalhes bibliográficos
Main Authors: Moormann, Ann M., Heller, Kevin N., Chelimo, Kiprotich, Embury, Paula, Ploutz-Snyder, Robert, Otieno, Juliana A., Oduor, Margaret, Münz, Christian, Rochford, Rosemary
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708320/
https://ncbi.nlm.nih.gov/pubmed/19089927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24014
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