PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse

Imprinted genes are important in development and their allelic expression is mediated by imprinting control regions (ICRs). On their DNA-methylated allele, ICRs are marked by trimethylation at H3 Lys 9 (H3K9me3) and H4 Lys 20 (H4K20me3), similar to pericentric heterochromatin. Here, we investigate w...

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Dettagli Bibliografici
Autori principali: Pannetier, Maëlle, Julien, Eric, Schotta, Gunnar, Tardat, Mathieu, Sardet, Claude, Jenuwein, Thomas, Feil, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Scientific Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525564/
https://ncbi.nlm.nih.gov/pubmed/18724273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.147
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