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B Lymphocytes Producing Demyelinating Autoantibodies: Development and Function in Gene-targeted Transgenic Mice

We studied the cellular basis of self tolerance of B cells specific for brain autoantigens using transgenic mice engineered to produce high titers of autoantibodies against the myelin oligodendrocyte glycoprotein (MOG), a surface component of central nervous system myelin. We generated “knock-in” mi...

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Bibliographische Detailangaben
Hauptverfasser: Litzenburger, Tobias, Fässler, Reinhard, Bauer, Jan, Lassmann, Hans, Linington, Christopher, Wekerle, Hartmut, Iglesias, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525547/
https://ncbi.nlm.nih.gov/pubmed/9653093
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