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Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Leucine Biosynthesis in Prototrophic and Leucine Auxotrophic Strains

The first enzyme in the biosynthesis of leucine in yeast, α-isopropylmalate synthetase, is inhibited by l-leucine. In a mutant resistant to the analogue 5′,5′,5′-trifluoroleucine, the enzyme is markedly resistant to inhibition by l-leucine. Growth ing the presence of exogenous l-leucine results in r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Satyanarayana, T., Umbarger, H. E., Lindegren, Gertrude
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1968
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC252553/
https://ncbi.nlm.nih.gov/pubmed/5724970
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