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Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Leucine Biosynthesis in Prototrophic and Leucine Auxotrophic Strains

The first enzyme in the biosynthesis of leucine in yeast, α-isopropylmalate synthetase, is inhibited by l-leucine. In a mutant resistant to the analogue 5′,5′,5′-trifluoroleucine, the enzyme is markedly resistant to inhibition by l-leucine. Growth ing the presence of exogenous l-leucine results in r...

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Bibliografske podrobnosti
izdano v:J Bacteriol
Main Authors: Satyanarayana, T., Umbarger, H. E., Lindegren, Gertrude
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1968
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5724970/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.96.6.2018-2024.1968
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