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Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Leucine Biosynthesis in Prototrophic and Leucine Auxotrophic Strains
The first enzyme in the biosynthesis of leucine in yeast, α-isopropylmalate synthetase, is inhibited by l-leucine. In a mutant resistant to the analogue 5′,5′,5′-trifluoroleucine, the enzyme is markedly resistant to inhibition by l-leucine. Growth ing the presence of exogenous l-leucine results in r...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1968
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC252553/ https://ncbi.nlm.nih.gov/pubmed/5724970 |
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