Demonstration of an immunodominant neutralization site by analysis of antigenic variants of SA11 rotavirus.

Serotype-specific monoclonal antibodies were used to select mutants of SA11 rotavirus that were resistant to neutralization. The antigenic characteristics of these mutants were studied with with a panel of monoclonal antibodies. We isolated one type of mutant which showed a dramatic increase (greate...

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Publicat a:J Virol
Autors principals: Lazdins, I, Sonza, S, Dyall-Smith, M L, Coulson, B S, Holmes, I H
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1985
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252539/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2993661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.56.1.317-319.1985
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