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Demonstration of an immunodominant neutralization site by analysis of antigenic variants of SA11 rotavirus.

Serotype-specific monoclonal antibodies were used to select mutants of SA11 rotavirus that were resistant to neutralization. The antigenic characteristics of these mutants were studied with with a panel of monoclonal antibodies. We isolated one type of mutant which showed a dramatic increase (greate...

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Autori principali: Lazdins, I, Sonza, S, Dyall-Smith, M L, Coulson, B S, Holmes, I H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC252539/
https://ncbi.nlm.nih.gov/pubmed/2993661
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