Alphavirus neurovirulence: monoclonal antibodies discriminating wild-type from neuroadapted Sindbis virus.

Wild-type Sindbis virus strain AR339 (SV) and a neurovirulent mutant (NSV), derived by neonatal and weanling mouse brain passage, both cause acute fatal encephalitis in neonatal mice, but NSV alone kills adult mice. NSV cannot be distinguished from SV by immune sera or simple biochemical tests. To l...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Stanley, J, Cooper, S J, Griffin, D E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2411947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.56.1.110-119.1985
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