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The Putative “Switch 2” Domain of the Ras-related GTPase, Rab1B, Plays an Essential Role in the Interaction with Rab Escort Protein

Posttranslational modification of Rab proteins by geranylgeranyltransferase type II requires that they first bind to Rab escort protein (REP). Following prenylation, REP is postulated to accompany the modified GTPase to its specific target membrane. REP binds preferentially to Rab proteins that are...

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Detalhes bibliográficos
Main Authors: Overmeyer, Jean H., Wilson, Amy L., Erdman, Robert A., Maltese, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25245/
https://ncbi.nlm.nih.gov/pubmed/9437002
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