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Charge density of divalent metal cations determines RNA stability
RNA molecules are exquisitely sensitive to the properties of counterions. The folding equilibrium of the Tetrahymena ribozyme is measured by non-denaturing gel electrophoresis in the presence of divalent group IIA metal cations. The stability of the folded ribozyme increases with the charge density...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2523262/ https://ncbi.nlm.nih.gov/pubmed/17295487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja068027r |
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