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Synthesis of a Biotin-Derived Alkyne for Pd-Catalyzed Coupling Reactions

[Image: see text] An efficient synthesis of a terminal alkyne derived from d-biotin was developed to provide an alternative for carboxylbased biotinylation. This approach was illustrated by the preparation of alkyne- and alkene-linked phenylalanine derivatives using palladium-catalyzed Sonogashira a...

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Autori principali: Corona, Cesear, Bryant, Bj K., Arterburn, Jeffrey B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2523258/
https://ncbi.nlm.nih.gov/pubmed/16623575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol060458r
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