Comparative Analysis of mRNA Targets for Human PUF-Family Proteins Suggests Extensive Interaction with the miRNA Regulatory System

Genome-wide identification of mRNAs regulated by RNA-binding proteins is crucial to uncover post-transcriptional gene regulatory systems. The conserved PUF family RNA-binding proteins repress gene expression post-transcriptionally by binding to sequence elements in 3′-UTRs of mRNAs. Despite their we...

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Bibliographic Details
Main Authors: Galgano, Alessia, Forrer, Michael, Jaskiewicz, Lukasz, Kanitz, Alexander, Zavolan, Mihaela, Gerber, André P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522278/
https://ncbi.nlm.nih.gov/pubmed/18776931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003164
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