Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

Virus-infected cells secrete a broad range of interferon (IFN) subtypes which in turn trigger the synthesis of antiviral factors that confer host resistance. IFN-α, IFN-β and other type I IFNs signal through a common universally expressed cell surface receptor, whereas IFN-λ uses a distinct receptor...

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Autors principals: Mordstein, Markus, Kochs, Georg, Dumoutier, Laure, Renauld, Jean-Christophe, Paludan, Søren R., Klucher, Kevin, Staeheli, Peter
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522277/
https://ncbi.nlm.nih.gov/pubmed/18787692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000151
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