A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis

In multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE), impairment of glial “Excitatory Amino Acid Transporters” (EAATs) together with an excess glutamate-release by invading immune cells causes excitotoxic damage of the central nervous system (CNS). In order...

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Main Authors: Melzer, Nico, Meuth, Sven G., Torres-Salazar, Delany, Bittner, Stefan, Zozulya, Alla L., Weidenfeller, Christian, Kotsiari, Alexandra, Stangel, Martin, Fahlke, Christoph, Wiendl, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522272/
https://ncbi.nlm.nih.gov/pubmed/18773080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003149
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